[PDF.02xq] Biomedical Informatics for Cancer Research

Biomedical Informatics for Cancer Research

[PDF.vb81] Biomedical Informatics for Cancer Research

Biomedical Informatics for Cancer From Brand: Springer US epub
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 | #7536958 in Books |  Springer US |  2010-04-01 | Original language:English | PDF # 1 |  9.20 x1.00 x6.10l,1.45 | File type: PDF | 354 pages

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||From the Back Cover|| |In the past two decades, the large investment in cancer research led to identification of the complementary roles of genetic mutation and epigenetic change as the fundamental drivers of cancer. With these discoveries, we now recognize the

view, showing that multiple molecular pathways must be affected for cancer to develop, but with different specific proteins in each pathway mutated or differentially expressed in a given tumor (The Cancer Genome Atlas Research Network 2008; Parsons et al. 2008). Different studies demonstrated that while widespread mutations exist in cancer, not all mutations drive cancer development (Lin et al. 2007). This suggests a need to target only a deleterious subset of aberrant p...

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